{"id":3077,"date":"2021-11-15T08:12:41","date_gmt":"2021-11-15T06:12:41","guid":{"rendered":"https:\/\/ita-suomenbiopankki.fi\/?post_type=tutkimus&p=3077"},"modified":"2021-12-14T08:15:04","modified_gmt":"2021-12-14T06:15:04","slug":"prognostic-impact-of-epithelial-mesenchymal-transition-transcription-factors-slug-zeb1-and-twist-in-t-cell-lymphomas-ptcl","status":"publish","type":"tutkimus","link":"https:\/\/blogs2.uef.fi\/itasuomenbiopankki-vanha\/tutkimus\/prognostic-impact-of-epithelial-mesenchymal-transition-transcription-factors-slug-zeb1-and-twist-in-t-cell-lymphomas-ptcl\/","title":{"rendered":"Prognostic impact of epithelial-mesenchymal -transition transcription factors SLUG, ZEB1 and TWIST in T-cell lymphomas (PTCL)"},"content":{"rendered":"

T-solulymfoomat ovat l\u00e4nsimaissa harvinaisen lymfooman alaryhm\u00e4. Niiden luokittelu ja biologia tunnetaan huonosti, mik\u00e4 heijastuu huonoina hoitotuloksina. Alustavissa tutkimuksissamme vaikuttaa, ett\u00e4 EMT \u2013markkerit SLUG ja TWIST kykenev\u00e4t erottamaan T-solulymfoomien joukosta aiemmin tuntemattoman huonoennusteisen alatyypin. T\u00e4m\u00e4n tutkimuksen tarkoituksena on toistaa n\u00e4m\u00e4 tulokset laajemmassa materiaalissa siten, ett\u00e4 se pystytt\u00e4isiin erottamaan muista lymfoomatyypeist\u00e4. My\u00f6hemmin on tarkoitus sekvensoinnein ja soluviljelymenetelmin tutkia t\u00e4m\u00e4n lymfoomatyypin biologiaa ja pyrki\u00e4 l\u00f6yt\u00e4m\u00e4\u00e4n siihen tehoavia l\u00e4\u00e4kkeit\u00e4. T\u00e4m\u00e4n tutkimuksen tieteellinen merkitys ja arvo on kuvata uusi, t\u00e4ll\u00e4 hetkell\u00e4 huonoennusteinen T-solulymfooma-alatyyppi ja l\u00f6yt\u00e4\u00e4 siihen parempia hoitoja ja pyrki\u00e4 parantamaan potilaita, jotka l\u00e4hes aina menehtyv\u00e4t nykyhoidoin lymfoomaansa.<\/p>\n","protected":false},"menu_order":0,"template":"","class_list":["post-3077","tutkimus","type-tutkimus","status-publish","hentry"],"acf":[],"yoast_head":"\nPrognostic impact of epithelial-mesenchymal -transition transcription factors SLUG, ZEB1 and TWIST in T-cell lymphomas (PTCL) - It\u00e4-Suomen biopankki<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs2.uef.fi\/itasuomenbiopankki-vanha\/tutkimus\/prognostic-impact-of-epithelial-mesenchymal-transition-transcription-factors-slug-zeb1-and-twist-in-t-cell-lymphomas-ptcl\/\" \/>\n<meta property=\"og:locale\" content=\"fi_FI\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Prognostic impact of epithelial-mesenchymal -transition transcription factors SLUG, ZEB1 and TWIST in T-cell lymphomas (PTCL) - It\u00e4-Suomen biopankki\" \/>\n<meta property=\"og:description\" content=\"T-solulymfoomat ovat l\u00e4nsimaissa harvinaisen lymfooman alaryhm\u00e4. 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